Atopic dermatitis (eczema) is a condition in which you suffer from itchiness and repetitive red skin rashes.
Atopic dermatitis is a chronic (continuous) skin condition with fluctuating symptom intensity.
It may be accompanied by asthma or hay fever.
Skin barrier function
The uppermost layer of the skin (stratum corneum) functions as ‘skin barrier’.
It prevents excessive water loss from the inside of the body as well as the invasion of external pathogens and allergens.
Therapeutic plans for atopic dermatitis
01Appropriate diagnosis of ‘atopic dermatitis’
02Remission introduction
- Topical steroid ointment
- Tacrolimus ointment (Protopic)
- Delgocitinib (Corectim)
- Supportive antihistamines
- Finding exacerbating factors
Responsive to therapy
03Remission maintenance
- Proactive therapy*
- Control of the dermatitis with tacrolimus or delgocitinib ointment.
*Proactive therapy : long –term, low-dose intermittent application of antiinflammatory therapy
Resistant to therapy
03Intractable state
- Ultraviolet therapy
- Cyclosporine: oral immunosuppressant**
- Dupilmab: injection therapy**
- Baricitinib
- Upadacitinib: oral JAK inhibitor
**These therapies are available at the clinic.
